Colonel Future became obsessed with ridding him of Clark Kent.  His next move was to send his agents to replace the movers that were helping the Kents re-locate to their new home.  After a couple of failed assassination attempts, the Kents confronted the criminals directly, pretending to reveal that Kent was Superman and then staging a ruse that made it appear that Superman had disguised himself as Kent to capture the criminals.  The would-be assassins were carted off to jail but Colonel Future remained free (Superman Vol.1 #327).

Some months later, Colonel Future was further enraged to see Clark Kent promoted to editor of the Daily Star, rewarding what Future saw as a rise fueled from opposing him.  He resolved to topple the entire building housing  the Star Office and planted a vibrational force field projector that would envelop the building and shake it to pieces with everyone inside.  Superman was initially thwarted at escaping but eventually identified a way to break through the field and capture Colonel Future and his men deploy the vibration beam.  Colonel Future was then taken to jail (Superman Family #198).

Later still, Colonel Future was once again free and returning to his roots of futuristic science.  He developed a weapon designed to drain Superman of the solar energy that gave him his powers and started a robbery at the Fourth National Bank.  As Superman swooped in to engage, Future discharged his weapons, sapping Superman’s strength and ability to fly and then deploying a robot device with heat-vision proof bindings.   Unknown to Future, the Kents had been caring for Liandli, an alien girl from the planet Rolez who also possessed awesome powers on Earth and her timely arrival freed the Man of Steel, who in turn promptly turned the tide against Colonel Future and his men (Superman #220).

The fate of Colonel Future on Earth-Two remains unrevealed.