After a restless night, Superman , as Clark Kent, arrives to the Daily Planet to find his co-workers frozen in place.  Changing to Superman, he learns the entirety of Metropolis is likewise paralyzed and seeing the Evil Three racing around the city, he knows they must be the source.  Using his super-hearing, he follows a low-frequency sound to a machine on a distance mountain top. Destroying the machine restores the citizen of Metropolis and Superman returns to challenge the brothers from looting labs around the city..  The Kryptonians agree that only a battle royale will  settle the score and they adjourn to an uninhabited island to fight it out.  Superman, more experience with  his powers, holds his own against the three but cannot get the upper hand, even as the battle creates seismic impact measurable all over the world.  Realizing brawn enough is not the answer, Superman use his super-ventriloquism to trick the brothers into believe each had insulted the other, resulting in their fighting among themselves.  When they eventually exhaust themselves, a recovered Superman returns and uses Jor-L formulas to recreate their rocket prison.  He sends them into space, hoping never to see them again (Superman #65).

Such  was not his luck however, as a few years later in 1954, the ship bearing the three brothers is again struck by a meteor and crashes it, free the three.  While two brother decide to use their new-found freedom to escape, Mala insists on seeking vengeance against Superman.  Returning to Earth, Mala decides to impersonate Clark Kent, not realizing that "Superman's Friend" is in fact, Superman himself.  Thinking he has disposed of Kent, Mala arrives at the Planet but his quick temper and undisguised powers raise suspicions.  The following day, Mala goes on a crime spree, stealing the Earth's monuments.  Superman intervenes but Mala's threats of destruction allow him to escape. 

Returning to his Clark Kent impersonation, Mala and Lois are ambushed by local thugs, causing "Clark" to reveal his super=powers.  Mala quickly claims that "Clark Kent is Superman" not realizing he has inadvertently revealed Superman's secret.  Superman meanwhile is attempting to restore the stolen monuments to their correct locations.  "Clark Kent" offers Lois the scoop of being revealed as Superman but instead reveals he is Mala and kidnaps her into space.  Superman returns and gives chase and Mala appears to counter him by flinging the globe containing Lois toward the Earth.  Superman catches her but they find an Earth with monuments but no life.  Superman soon realizes  that the Earth is fake and destroys it, returning to find the Mala has summoned his two brothers to Metropolis. 

Swearing to destroy the Earth, robbing Superman of a home a second time, the three brothers are enraged to see Superman approached in a bubble-shaped craft.  The quickly rush inside to confront him but find only a stuffed dummy and themselves trapped inside.  Before they can break free, Superman arrives with a basket held at some distance.  He empties that basket and uses his super-breath to blast into the surface of the craft, revealing into be fragments of Kryptonite that weaken and traps the brothers.   Superman then hurls the shift into the depths of space with the admonition to never return (Action Comics #194).

The fate of the Evil Three have never been revealed.